Anal cancer: Symptoms, causes, and treatments - How can you get anal cancer Like 94.97% | 939 votes Views: 557 508 Download Older age. Most cases of. Many sexual partners. Categories: Cuckhold Comments: Add Comment Cancel By Shakataxe - 22:03 Human papillomavirus (HPV). By Nagrel - 19:07 Drugs or conditions that suppress your immune system. By Tojajar - 02:36 Anal cancer is an uncommon type of cancer that occurs in the anal canal. Anal cancer can cause signs and symptoms such as rectal bleeding and anal pain. Anal cancer is closely related to a sexually transmitted infection called human papillomavirus (HPV).